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The Effect of Human Immunodeficiency Virus-1 Infection on Low Birth Weight, Mother to Child HIV Transmission and Infants’ Death in African Area


Background: It is yet a controversy subject whether low birth weight and infantdeath are associated to human immunodeficiency virus-1 infection. Objective: To appreciate association between low birth weights, mother to child HIVtransmission and infant mortality in HIV-1 infected pregnant women deliveringbetween 2011 and 2016. Materials: We conducted 6 years cohort study inurban Mali. Outcome included preterm delivery, small for gestational age,infant survival status and HIV transmission. Comparison concerned womenclinical WHO stage, mother viro-immunological status, and newborn anthropometric parameters. Results: HIV-1 infected womenwho delivered low birth weight newborn were 20.9% (111/531) versus 16.5%(1910/11.546) in HIV negative patients (p = 0.016). CD4 T cell counts low than350 T cells count were strongly associated to LBW (p = 0.000; RR = 3.03; 95% CI [1.89 - 3.16]).There is no significant association between ART that was initiated duringpregnancy (p = 0.061, RR = 0.02; CI 95% (......

【作者名称】: Traoré Youssouf, Téguété Ibrahima, Dicko Fatoumata Traoré, Bocoum Amadou, Fané Seydou, Traoré Tidiani
【关 键 词】: Low Birth Weight, Human Immunodeficiency Virus, Infection, Mother to Child Transmission, Newborn Death, Mali
【网站名称】: 美国科学研究出版社
【期刊论文数据库】: [DBS_Articles_01]
【期刊论文编号】: 103,355,259
【摘要长度】: 1,000
【栏目名称】: 期刊
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