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Clinical Cytomics


The goal of predictive medicine is the detection of changes in patient's state prior to the clinical manifestation of the deterioration of the patients current status. Therefore, both the diagnostic of diseases like cancer, coronary atherosclerosis or congenital heart failure and the prognosis of the effect specific therapeutics on patients outcome are the main fields of predictive medicine. Clinical Cytomcs is based on the analysis of specimens from the patient by Cytomic technologies that are mainly imaging based techniques and their combinations with other assays. Predictive medicine aims at the recognition of the 'fate' of each individual patients in order to yield unequivocal indications for decision making (i.e. how does the patient respond to therapy, react to medication etc.). This individualized prediction is based on the Predictive Medicine by Clinical Cytomics concept. These considerations have recently stimulated the idea of the Human Cytome Project. A major focus of the Human Cytome Project is multiplexed cytomic analysis of individual cells of the patient, extraction of predictive information and individual prediction that merges into individualized therapy. Although still at the beginning, Clinical Cytomics is a promising new field that may change therapy in the near future for the benefit of the patients.......

【作者名称】: Attila Tarnok, Anja Mittag, Dominik Lenz
【作者单位】: Dept. of Pediatric Cardiology, Cardiac Center Leipzig, University of Leipzig, Struempellstr. 39 D-04289 Leipzig, Germany
【关 键 词】: slide based cytometry, laser scanning cytometry, image analysis, individualized medicine
【会议名称】: Imaging, Manipulation, and Analysis of Biomolecules, Cells and Tissues IV; Progress in Biomedical Optics and Imaging; vol.7 no.11
【期刊论文数据库】: [DBS_Articles_01]
【期刊论文编号】: 100,998,947
【摘要长度】: 1,342
【会议地点】: San Jose,CA(US)
【会议组织】: Dept. of Pediatric Cardiology, Cardiac Center Leipzig, University of Leipzig, Struempellstr. 39 D-04289 Leipzig, Germany
【会议时间】: 2006
【上篇论文】: 外文会议 - Multimodal Nonlinear Optical Microscopy used to Discriminate Human Colon Cancer
【下篇论文】: 外文会议 - Serum LDL-Cholesterol-Lowering Effects of a Mixed Green Vegetable and Fruit Beverage Containing Broccoli and Cabbage in Humans

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